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Effect of Pentoxifylline on Tumor Suppressor and Proto-Oncogene Apoptosis in Sperm

Purpose: Pentoxifylline (PTX), a methylxanthine phosphodiesterase inhibitor reduces superoxide anions responsible for DNA apoptosis. The null hypothesis was that PTX was equally effective in reducing damage to specific cell genes. The objective was to determine the DNA integrity of the BRCA1 tumor s...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Maxwell, David T., Jacobson, John D., King, Alan, Chan, Philip J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Kluwer Academic Publishers-Plenum Publishers 2002
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3455213/
https://ncbi.nlm.nih.gov/pubmed/12166633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1023/A:1015725230011
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