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RNA-DNA differences are rarer in proto-oncogenes than in tumor suppressor genes

It has long been assumed that DNA sequences and corresponding RNA transcripts are almost identical; a recent discovery, however, revealed widespread RNA-DNA differences (RDDs), which represent a largely unexplored aspect of human genome variation. It has been speculated that RDDs can affect disease...

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Detalhes bibliográficos
Main Authors: Gao, Feng, Lin, Yan, Zhang, Randy Ren
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3270091/
https://ncbi.nlm.nih.gov/pubmed/22355757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00245
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