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Destruction of Protamine in Human Sperm Inhibits Sperm Binding and Penetration in the Zona-Free Hamster Penetration Test but Increases Sperm Head Decondensation and Male Pronuclear Formation in the Hamster–ICSI Assay

Purpose:Our purpose was to investigate the fertilizing ability of human protamine-damaged sperm in a heterologous system using hamster oocytes. Methods:The protamine of the sperm were damaged by exposure to dithiothreitol, a disulfide-reducing agent. Their ability to penetrate and form male pronucle...

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Detalhes bibliográficos
Main Authors: Ahmadi, Ali, Ng, Soon-Chye
Formato: Artigo
Idioma:Inglês
Publicado em: Kluwer Academic Publishers-Plenum Publishers 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3455208/
https://ncbi.nlm.nih.gov/pubmed/10091115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1023/A:1022527714175
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