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Destruction of Protamine in Human Sperm Inhibits Sperm Binding and Penetration in the Zona-Free Hamster Penetration Test but Increases Sperm Head Decondensation and Male Pronuclear Formation in the Hamster–ICSI Assay
Purpose:Our purpose was to investigate the fertilizing ability of human protamine-damaged sperm in a heterologous system using hamster oocytes. Methods:The protamine of the sperm were damaged by exposure to dithiothreitol, a disulfide-reducing agent. Their ability to penetrate and form male pronucle...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Kluwer Academic Publishers-Plenum Publishers
1999
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3455208/ https://ncbi.nlm.nih.gov/pubmed/10091115 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1023/A:1022527714175 |
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