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Coilin levels modulate cell cycle progression and γH2AX levels in etoposide treated U2OS cells

Coilin is considered the Cajal body (CB) marker protein. In this report, we investigated the role of coilin in the DNA damage response and found that coilin reduction correlated with significantly increased levels of soluble γH2AX in etoposide treated U2OS cells. Additionally, coilin levels influenc...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Velma, Venkatramreddy, Carrero, Zunamys I., Allen, Carmen B., Hebert, Michael D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3455142/
https://ncbi.nlm.nih.gov/pubmed/22986342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2012.07.054
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