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Mechanism of insertion of diphtheria toxin: peptide entry and pore size determinations.

Diphtheria toxin ( DTx ) is an extremely potent inhibitor of protein synthesis. It is secreted as a linear polypeptide, which is cleaved to produce disulfide-linked A and B fragments. Fragment A, the inhibitor of protein synthesis, requires fragment B, the recognition subunit, for entry into intact...

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Bibliografische gegevens
Hoofdauteurs: Zalman, L S, Wisnieski, B J
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1984
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC345503/
https://ncbi.nlm.nih.gov/pubmed/6328510
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