Mechanism of insertion of diphtheria toxin: peptide entry and pore size determinations.
Diphtheria toxin ( DTx ) is an extremely potent inhibitor of protein synthesis. It is secreted as a linear polypeptide, which is cleaved to produce disulfide-linked A and B fragments. Fragment A, the inhibitor of protein synthesis, requires fragment B, the recognition subunit, for entry into intact...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1984
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC345503/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6328510/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.11.3341 |
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