Concurrent Expression of MYC and BCL2 in Diffuse Large B-Cell Lymphoma Treated With Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone

PURPOSE: Diffuse large B-cell lymphoma (DLBCL) is curable in 60% of patients treated with rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP). MYC translocations, with or without BCL2 translocations, have been associated with inferior survival in DLBCL. We investigated...

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Main Authors: Johnson, Nathalie A., Slack, Graham W., Savage, Kerry J., Connors, Joseph M., Ben-Neriah, Susana, Rogic, Sanja, Scott, David W., Tan, King L., Steidl, Christian, Sehn, Laurie H., Chan, Wing C., Iqbal, Javeed, Meyer, Paul N., Lenz, Georg, Wright, George, Rimsza, Lisa M., Valentino, Carlo, Brunhoeber, Patrick, Grogan, Thomas M., Braziel, Rita M., Cook, James R., Tubbs, Raymond R., Weisenburger, Dennis D., Campo, Elias, Rosenwald, Andreas, Ott, German, Delabie, Jan, Holcroft, Christina, Jaffe, Elaine S., Staudt, Louis M., Gascoyne, Randy D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2012
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ORIGINAL REPORTS
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3454768/
https://ncbi.nlm.nih.gov/pubmed/22851565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2011.41.0985
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