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Monocytes from Irf5(−/−) mice have an intrinsic defect in their response to pristane-induced lupus
The transcription factor interferon regulatory factor 5 (IRF5) has been identified as a human systemic lupus erythematosus (SLE) susceptibility gene by numerous joint linkage and genome-wide association studies. Although IRF5 expression is significantly elevated in primary blood cells of SLE patient...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3454479/ https://ncbi.nlm.nih.gov/pubmed/22933628 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201162 |
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