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Monocytes from Irf5(−/−) mice have an intrinsic defect in their response to pristane-induced lupus

The transcription factor interferon regulatory factor 5 (IRF5) has been identified as a human systemic lupus erythematosus (SLE) susceptibility gene by numerous joint linkage and genome-wide association studies. Although IRF5 expression is significantly elevated in primary blood cells of SLE patient...

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Detalhes bibliográficos
Main Authors: Yang, Lisong, Feng, Di, Bi, Xiaohui, Stone, Rivka C., Barnes, Betsy J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3454479/
https://ncbi.nlm.nih.gov/pubmed/22933628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201162
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