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Age-Associated Hyper-Methylated Regions in the Human Brain Overlap with Bivalent Chromatin Domains

Recent associations between age-related differentially methylated sites and bivalently marked chromatin domains have implicated a role for these genomic regions in aging and age-related diseases. However, the overlap between such epigenetic modifications has so far only been identified with respect...

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Detalhes bibliográficos
Main Authors: Watson, Corey T., Disanto, Giulio, Sandve, Geir Kjetil, Breden, Felix, Giovannoni, Gavin, Ramagopalan, Sreeram V.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3454416/
https://ncbi.nlm.nih.gov/pubmed/23028473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043840
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