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Use of peptide synthesis to probe viral antigens for epitopes to a resolution of a single amino acid.

A procedure is described for rapid concurrent synthesis on solid supports of hundreds of peptides, of sufficient purity to react in an enzyme-linked immunosorbent assay. Interaction of synthesized peptides with antibodies is then easily detected without removing them from the support. In this manner...

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Detalhes bibliográficos
Main Authors: Geysen, H M, Meloen, R H, Barteling, S J
Formato: Artigo
Idioma:Inglês
Publicado em: 1984
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC345355/
https://ncbi.nlm.nih.gov/pubmed/6204335
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