Carnitine palmitoyltransferase 1A (CPT1A): a transcriptional target of PAX3-FKHR and mediates PAX3-FKHR–dependent motility in alveolar rhabdomyosarcoma cells

BACKGROUND: Alveolar rhabdomyosarcoma (ARMS) has a high propensity to metastasize, leading to its aggressiveness and a poor survival rate among those with the disease. More than 80% of aggressive ARMSs harbor a PAX3-FKHR fusion transcription factor, which regulates cell migration and promotes metast...

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Main Authors: Liu, Lingling, Wang, Yong-Dong, Wu, Jing, Cui, Jimmy, Chen, Taosheng
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2012
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3453510/
https://ncbi.nlm.nih.gov/pubmed/22533991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-154
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