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A novel ligand delivery system to non-invasively visualize and therapeutically exploit the IL13Rα2 tumor-restricted biomarker

Our objective was to exploit a novel ligand-based delivery system for targeting diagnostic and therapeutic agents to cancers that express interleukin 13 receptor alpha 2 (IL13Rα2), a tumor-restricted plasma membrane receptor overexpressed in glioblastoma multiforme (GBM), meningiomas, peripheral ner...

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Detalhes bibliográficos
Main Authors: Nguyen, Van, Conyers, Jesse M., Zhu, Dongqin, Gibo, Denise M., Hantgan, Roy R., Larson, Steven M., Debinski, Waldemar, Mintz, Akiva
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3452345/
https://ncbi.nlm.nih.gov/pubmed/22952195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nos211
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