Tumor promoters block tyrosine-specific phosphorylation of the epidermal growth factor receptor.

Tyrosine-specific phosphorylation of the epidermal growth factor (EGF) receptor in hormonally stimulated A431 cells is blocked by three chemically distinct classes of tumor promoters. Tumor-promoting esters of the diterpene phorbol (phorbol 12-myristate 13-acetate, beta-phorbol 12,13-dibutyrate, and...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Friedman, B, Frackelton, A R, Ross, A H, Connors, J M, Fujiki, H, Sugimura, T, Rosner, M R
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1984
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Research Article
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC345215/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6328489/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.10.3034
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