beta-Thalassemia in Chinese: use of in vivo RNA analysis and oligonucleotide hybridization in systematic characterization of molecular defects.

To perform a systematic analysis of beta-thalassemia genes among Chinese, we have determined the DNA haplotype in the beta-globin gene region of 37 Chinese beta-thalassemia chromosomes. Only four haplotypes were found. Blot hybridization analysis of erythroid RNA from patients homozygous for haploty...

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-д хэвлэсэн:	Proc Natl Acad Sci U S A
Үндсэн зохиолчид:	Cheng, T C, Orkin, S H, Antonarakis, S E, Potter, M J, Sexton, J P, Markham, A F, Giardina, P J, Li, A, Kazazian, H H
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	National Academy of Sciences 1984
Нөхцлүүд:	Research Article
Онлайн хандалт:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC345162/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6585831/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.9.2821
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