Neuron-Specific Enolase Is Elevated in Asymptomatic Carriers of Leber's Hereditary Optic Neuropathy

PURPOSE. Neuron-specific enolase (NSE) is a biomarker for neuronal stress. Leber's hereditary optic neuropathy (LHON) is a mitochondrial disease affecting retinal ganglion cells (RGC). These RGCs and their axons in the retinal nerve fiber layer (RNFL) and optic nerve head may show subclinical p...

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Detalhes bibliográficos
Main Authors: Yee, Kenneth M., Ross-Cisneros, Fred N., Lee, Jeong Goo, Da Rosa, Arlon Bastos, Salomao, Solange R., Berezovsky, Adriana, Belfort, Rubens, Chicani, Filipe, Moraes-Filho, Milton, Sebag, Jerry, Carelli, Valerio, Sadun, Alfredo A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3450916/
https://ncbi.nlm.nih.gov/pubmed/22893673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.12-9677
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