Variations in DNA methylation during mouse cell differentiation in vivo and in vitro.

Mouse teratocarcinoma cells induced to differentiate in vitro undergo a massive (30%) demethylation of DNA. A similar undermethylation is also observed in the mouse extraembryonic membranes, the yolk sac and placenta. In both cases, the decrease in methyl moieties occurs at a large number of CpG sit...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Razin, A, Webb, C, Szyf, M, Yisraeli, J, Rosenthal, A, Naveh-Many, T, Sciaky-Gallili, N, Cedar, H
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1984
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Research Article
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC345041/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6585800/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.8.2275
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