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Variations in DNA methylation during mouse cell differentiation in vivo and in vitro.
Mouse teratocarcinoma cells induced to differentiate in vitro undergo a massive (30%) demethylation of DNA. A similar undermethylation is also observed in the mouse extraembryonic membranes, the yolk sac and placenta. In both cases, the decrease in methyl moieties occurs at a large number of CpG sit...
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| 出版年: | Proc Natl Acad Sci U S A |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
1984
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC345041/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6585800/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.8.2275 |
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