Variations in DNA methylation during mouse cell differentiation in vivo and in vitro.

Mouse teratocarcinoma cells induced to differentiate in vitro undergo a massive (30%) demethylation of DNA. A similar undermethylation is also observed in the mouse extraembryonic membranes, the yolk sac and placenta. In both cases, the decrease in methyl moieties occurs at a large number of CpG sit...

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Hlavní autoři: Razin, A, Webb, C, Szyf, M, Yisraeli, J, Rosenthal, A, Naveh-Many, T, Sciaky-Gallili, N, Cedar, H
Médium: Artigo
Jazyk:Inglês
Vydáno: 1984
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC345041/
https://ncbi.nlm.nih.gov/pubmed/6585800
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