Class II HLA-DC beta-chain DNA restriction fragments differentiate among HLA-DR2 individuals in insulin-dependent diabetes and multiple sclerosis.

HLA-DR2 allele is negatively associated with insulin-dependent diabetes and positively associated with multiple sclerosis (MS). A 2.2-kilobase-pair EcoRI DNA restriction fragment detected with a beta-chain HLA-DC cDNA probe was found to be strongly correlated with HLA-DR2 in the normal population, b...

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Hauptverfasser: Cohen, D, Cohen, O, Marcadet, A, Massart, C, Lathrop, M, Deschamps, I, Hors, J, Schuller, E, Dausset, J
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1984
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC345003/
https://ncbi.nlm.nih.gov/pubmed/6324215
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