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Serum-free production of a chimeric E-selectin-IgG protein from 1 to 100 l scale: Repeated batch cultivation versus continuous spin filter perfusion

On inflamed endothelium the cell surface protein E-selectin isexpressed which supports the initial process of attachment –capturing and rolling of leukocytes. A recombinant CHO cell linesecreting a soluble E-selectin-IgG chimera was cultivated competitively under serum free conditions in three diffe...

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Библиографические подробности
Главные авторы: Werner, Andreas, Lütkemeyer, Dirk, Poggendorf, Iris, Lehmann, Jürgen, Müthing, Johannes
Формат: Artigo
Язык:Inglês
Опубликовано: Kluwer Academic Publishers 2002
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3449925/
https://ncbi.nlm.nih.gov/pubmed/19003086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1023/A:1021145813253
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