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Improvement of a cytokine (TNF-α) bioassay by serum-free target cell (WEHI 164) cultivation

The elaboration of a sensitive bioassay for assessment of tumour necrosis factor alpha (TNF-α) in a defined medium is described. The assay is based on the cytotoxic effect of TNF-α on a target cell line, the murine fibrosarcoma WEHI 164 clone 13. Cytotoxicity was assessed by detecting the rate of te...

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Detalhes bibliográficos
Main Authors: Figenschau, Yngve, Sveinbjörnsson, Baldur, Bertheussen, Kjell
Formato: Artigo
Idioma:Inglês
Publicado em: Kluwer Academic Publishers 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3449908/
https://ncbi.nlm.nih.gov/pubmed/22359061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1023/A:1008052307547
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