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Productivity enhancement of recombinant protein in CHO cells via specific promoter activation by oncogenes
To construct a recombinant protein highly producing cell lines, we have previously developed the Oncogene Activated Production (OAP) system by using BHK-21 cells. Here we verified the availability of the OAP system in CHO cells. We firstly generated ‘primed’ ras amplified CHO cells, ras clone I, by...
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| Asıl Yazarlar: | , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Kluwer Academic Publishers
1999
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3449785/ https://ncbi.nlm.nih.gov/pubmed/19003130 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1023/A:1008048928053 |
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