Formation of porcine hepatocyte spherical multicellular aggregates (spheroids) and analysis of drug metabolic functions

Porcine hepatocytes are used in the hybrid artificial liver support system that we are developing because of their high level of liver functions in vitro and because human hepatocytes can not be used in Japan for ethical reasons. Spherical multicellular aggregates or spheroids have been found to be...

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Bibliographic Details
Main Authors: Nakazawa, Kohji, Mizumoto, Hiroshi, Kaneko, Mitsuru, Ijima, Hiroyuki, Gion, Tomonobu, Shimada, Mitsuo, Shirabe, Ken, Takenaka, Kenji, Sugimachi, Keizo, Funatsu, Kazumori
Format: Artigo
Language:Inglês
Published: Kluwer Academic Publishers 1999
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3449777/
https://ncbi.nlm.nih.gov/pubmed/19003125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1023/A:1008040726236
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