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Determining subcellular localization of novel drug targets by transient transfection in COS cells

Genomics-based approaches are increasingly being used to identify disease-associated genes that represent potential new drug targets. As a first step in the validation of genes of unknown function, we describe a method for rapidly determining the subcellular localization of the gene product. If an i...

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Hlavní autoři: Simon, Iris, Wright, Meredith, Flohr, Tanya, Hevezi, Peter, Caras, Ingrid W.
Médium: Artigo
Jazyk:Inglês
Vydáno: Kluwer Academic Publishers 2001
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3449706/
https://ncbi.nlm.nih.gov/pubmed/22358858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1023/A:1013152432069
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