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Metabolic-flux analysis of hybridoma cells under oxidative and reductive stress using mass balances

Hybridoma cells were grown at steady state under both reductiveand oxidative stress and the intracellular fluxes weredetermined by mass-balancing techniques. By decreasing the dissolved oxygen pressure (pO(2)) in the bioreactor, the reduced formof nicotinamide adenine nucleotide (NADH) was enhanced...

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Detalhes bibliográficos
Main Authors: Bonarius, Hendrik P.J., Houtman, José H.M., Schmid, Georg, de Gooijer, Cornelis D., Tramper, Johannes
Formato: Artigo
Idioma:Inglês
Publicado em: Kluwer Academic Publishers 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3449692/
https://ncbi.nlm.nih.gov/pubmed/19002972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1023/A:1008142218103
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