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Mechanisms of resistance to alkylating agents

Alkylating agents are the most widely used anticancer drugs whose main target is the DNA, although how exactly the DNA lesions cause cell death is still not clear. The emergence of resistance to this class of drugs as well as to other antitumor agents is one of the major causes of failure of cancer...

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Detalles Bibliográficos
Main Authors: Damia, G., D‘Incalci, M.
Formato: Artigo
Idioma:Inglês
Publicado: Kluwer Academic Publishers 1998
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3449574/
https://ncbi.nlm.nih.gov/pubmed/19002790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1023/A:1008060720608
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