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Mechanisms of resistance to alkylating agents
Alkylating agents are the most widely used anticancer drugs whose main target is the DNA, although how exactly the DNA lesions cause cell death is still not clear. The emergence of resistance to this class of drugs as well as to other antitumor agents is one of the major causes of failure of cancer...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Kluwer Academic Publishers
1998
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3449574/ https://ncbi.nlm.nih.gov/pubmed/19002790 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1023/A:1008060720608 |
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