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Incidence and potential implications of the toxic metabolite methylglyoxal in cell culture: A review
Methylglyoxal is a toxic metabolite unavoidably produced in mammalian systems as a by-product of glycolysis. Detoxification of this compound occurs principally through the glyoxalase pathway, which consists of glyoxalase I and glyoxalase II, and requires reduced glutathione as a co-enzyme. Recently,...
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| Materialtyp: | Artigo |
| Språk: | Inglês |
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Kluwer Academic Publishers
1998
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| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3449548/ https://ncbi.nlm.nih.gov/pubmed/22358615 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1023/A:1007953628840 |
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