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Calcium-phosphate mediated DNA transfer into HEK-293 cells in suspension: control of physicochemical parameters allows transfection in stirred media. Transfection and protein expression in mammalian cells

This is the first report of transient transfection of suspended cells with purified plasmid DNA in bioreactors or spinner flasks. DNA/calcium phosphate complexes were pumped or injected directly into stirred cultures of the immortalized human embryo kidney cell line 293 (HEK-293) which had been adap...

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Hlavní autoři: Jordan, Martin, Köhne, Christiane, Wurm, Florian M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Kluwer Academic Publishers 1998
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3449510/
https://ncbi.nlm.nih.gov/pubmed/22359005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1023/A:1007917318181
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