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4-Hydroxy-2-Nonenal, a Reactive Product of Lipid Peroxidation, and Neurodegenerative Diseases: A Toxic Combination Illuminated by Redox Proteomics Studies

Significance: Among different forms of oxidative stress, lipid peroxidation comprises the interaction of free radicals with polyunsaturated fatty acids, which in turn leads to the formation of highly reactive electrophilic aldehydes. Among these, the most abundant aldehydes are 4-hydroxy-2-nonenal (...

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Detalhes bibliográficos
Main Authors: Perluigi, Marzia, Coccia, Raffaella, Butterfield, D. Allan
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3449441/
https://ncbi.nlm.nih.gov/pubmed/22114878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2011.4406
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