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Cell cycle phase dependent productivity of a recombinant Chinese hamster ovary cell line
A Chinese Hamster Ovary cell line, CHO1-15(500), producing recombinant human tissue type plasminogen activator (tPA) via the dihydrofolate reductase (DHFR) amplification system, was studied in batch culture. In this system both DHFR and tPA are under the control of the strong constitutive viral SV40...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Kluwer Academic Publishers
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3449425/ https://ncbi.nlm.nih.gov/pubmed/19002865 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-006-9041-4 |
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