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Cell cycle phase dependent productivity of a recombinant Chinese hamster ovary cell line

A Chinese Hamster Ovary cell line, CHO1-15(500), producing recombinant human tissue type plasminogen activator (tPA) via the dihydrofolate reductase (DHFR) amplification system, was studied in batch culture. In this system both DHFR and tPA are under the control of the strong constitutive viral SV40...

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Bibliografiske detaljer
Main Authors: Dutton, Roshni L., Scharer, Jeno, Moo-Young, Murray
Format: Artigo
Sprog:Inglês
Udgivet: Kluwer Academic Publishers 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3449425/
https://ncbi.nlm.nih.gov/pubmed/19002865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-006-9041-4
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