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Cell cycle phase dependent productivity of a recombinant Chinese hamster ovary cell line

A Chinese Hamster Ovary cell line, CHO1-15(500), producing recombinant human tissue type plasminogen activator (tPA) via the dihydrofolate reductase (DHFR) amplification system, was studied in batch culture. In this system both DHFR and tPA are under the control of the strong constitutive viral SV40...

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Sonraí Bibleagrafaíochta
Main Authors: Dutton, Roshni L., Scharer, Jeno, Moo-Young, Murray
Formáid: Artigo
Teanga:Inglês
Foilsithe: Kluwer Academic Publishers 2007
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3449425/
https://ncbi.nlm.nih.gov/pubmed/19002865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-006-9041-4
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