Origin of the beta S-globin gene in blacks: the contribution of recurrent mutation or gene conversion or both.

In order to investigate the origin(s) of the mutation(s) leading to the beta S-globin gene in North American populations of African ancestry, we analyzed DNA polymorphisms in the beta-globin gene cluster in a large number of both beta A- and beta S-globin gene-bearing chromosomes in U.S. and Jamaica...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Antonarakis, S E, Boehm, C D, Serjeant, G R, Theisen, C E, Dover, G J, Kazazian, H H
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1984
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC344936/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6583683/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.3.853
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