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On the origin and spread of beta-thalassemia: recurrent observation of four mutations in different ethnic groups.

Seven beta-thalassemia genes were characterized after they were identified as candidates for previously undescribed mutations based upon the close association of DNA polymorphism haplotypes in the beta-globin gene cluster with specific ethnic mutations. The molecular defect in four of these genes wa...

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Detalhes bibliográficos
Main Authors: Wong, C, Antonarakis, S E, Goff, S C, Orkin, S H, Boehm, C D, Kazazian, H H
Formato: Artigo
Idioma:Inglês
Publicado em: 1986
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC386537/
https://ncbi.nlm.nih.gov/pubmed/3462712
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