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Protective effects of peroxisome proliferator-activated receptor agonists on human podocytes: proposed mechanisms of action

BACKGROUND AND PURPOSE: Peroxisome proliferator-activated receptor (PPAR) agonists exert anti-albuminuric effects. However, the nephroprotective effects of these drugs remain to be fully understood. We have investigated whether gemfibrozil, GW0742 and pioglitazone protect human podocytes against nut...

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Detalhes bibliográficos
Main Authors: Miglio, Gianluca, Rosa, Arianna Carolina, Rattazzi, Lorenza, Grange, Cristina, Camussi, Giovanni, Fantozzi, Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3449267/
https://ncbi.nlm.nih.gov/pubmed/22594945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2012.02026.x
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