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Enhanced Hepatocarcinogenicity Due to Agonists of Peroxisome Proliferator-Activated Receptors in Senescent Rats: Role of Peroxisome Proliferation, Cell Proliferation, and Apoptosis

Exposure to agonists of peroxisome proliferator-activated receptor alpha (PPARα) causes liver cancer in rodents, with aged animals being more susceptible than their younger counterparts to this effect. Treatment with these chemicals produced a five- to sevenfold higher yield of grossly visible hepat...

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Detalhes bibliográficos
Publicado no:ScientificWorldJournal
Main Authors: Youssef, Jihan, Badr, Mostafa
Formato: Artigo
Idioma:Inglês
Publicado em: TheScientificWorldJOURNAL 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6009486/
https://ncbi.nlm.nih.gov/pubmed/12805935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1100/tsw.2002.352
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