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The intensity of immune activation is linked to the level of CCR5 expression in human immunodeficiency virus type 1-infected persons

Immune activation is a main driver of AIDS- and non-AIDS-linked morbidities in the course of HIV-1 infection. As CCR5, the main HIV-1 co-receptor, is not only a chemokine receptor but also a co-activation molecule expressed at the surface of T cells, it could be directly involved in this immune acti...

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Autors principals: Portales, Pierre, Psomas, Katerina Christina, Tuaillon, Edouard, Mura, Thibault, Vendrell, Jean-Pierre, Eliaou, Jean-François, Reynes, Jacques, Corbeau, Pierre
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3449250/
https://ncbi.nlm.nih.gov/pubmed/22862553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2012.03609.x
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