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Benzodiazepines that bind at peripheral sites inhibit cell proliferation.

[3H]Ro5-4864 binds to mouse thymoma cells in a specific, saturable, and reversible manner. Scatchard analysis shows a single class of binding sites with a Kd of 4.4 nM and a Bmax of 477 fmol per 10(6) cells. This benzodiazepine binding site is of the peripheral type, based on the relative potencies...

詳細記述

保存先:
書誌詳細
主要な著者: Wang, J K, Morgan, J I, Spector, S
フォーマット: Artigo
言語:Inglês
出版事項: 1984
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC344914/
https://ncbi.nlm.nih.gov/pubmed/6322168
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