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Controlled rotation of the F(1)-ATPase reveals differential and continuous binding changes for ATP synthesis

F(1)-ATPase is an ATP-driven rotary molecular motor that synthesizes ATP when rotated in reverse. To elucidate the mechanism of ATP synthesis, we imaged binding and release of fluorescently labelled ADP and ATP while rotating the motor in either direction by magnets. Here we report the binding and r...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Adachi, Kengo, Oiwa, Kazuhiro, Yoshida, Masasuke, Nishizaka, Takayuki, Kinosita, Kazuhiko
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Pub. Group 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3449090/
https://ncbi.nlm.nih.gov/pubmed/22929779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms2026
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