Down-regulation of NR3A-containing NMDARs is required for synapse maturation and memory consolidation

NR3A is the only NMDA receptor (NMDAR) subunit that down-regulates sharply prior to the onset of sensitive periods for plasticity, yet the functional importance of this transient expression remains largely unknown. To investigate the possibility that removal/replacement of juvenile NR3A-containing N...

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Autors principals: Roberts, Adam C., Díez-García, Javier, Rodriguiz, Ramona M., López, Iciar Paula, Luján, Rafael, Martínez-Turrillas, Rebeca, Picó, Esther, Henson, Maile A., Bernardo, Danilo R., Jarrett, Thomas M., Clendeninn, Dallis J., López-Mascaraque, Laura, Feng, Guoping, Lo, Donald C., Wesseling, John F., Wetsel, William C., Philpot, Benjamin D., Pérez-Otaño, Isabel
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448958/
https://ncbi.nlm.nih.gov/pubmed/19679074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2009.06.016
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