Nr3a-containing NMDA receptors promote neurotransmitter release and spike timing-dependent plasticity

Recent evidence suggests that presynaptic-acting NMDA receptors (preNMDARs) are important for neocortical synaptic transmission and plasticity. We found that unique properties of the Nr3a subunit enable preNMDARs to enhance spontaneous and evoked glutamate release and that Nr3a is required for spike...

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Detalhes bibliográficos
Main Authors: Larsen, Rylan S., Corlew, Rebekah J., Henson, Maile A., Roberts, Adam C., Mishina, Masayoshi, Watanabe, Masahiko, Lipton, Stuart A., Nakanishi, Nobuki, Pérez-Otaño, Isabel, Weinberg, Richard J., Philpot, Benjamin D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3474337/
https://ncbi.nlm.nih.gov/pubmed/21297630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2750
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