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Cullin RING Ligases: Glommed by Glomulin

Cullin ring ligases (CRLs) constitute the largest group of RING finger ubiquitin ligases. Two recent studies in Molecular Cell describe glomulin as a CRL1 inhibitor that blocks interactions with its ubiquitin-conjugating enzyme (E2) (Duda et al., 2012; Tron et al., 2012). These findings and their si...

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Autors principals: Hristova, Ventzislava A., Stringer, Daniel K., Weissman, Allan M.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448943/
https://ncbi.nlm.nih.gov/pubmed/22883621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.07.025
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