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The natural product cucurbitacin E inhibits depolymerization of actin filaments

Although small molecule actin modulators have been widely used as research tools, only one cell permeable small molecule inhibitor of actin depolymerization (jasplakinolide) is commercially available. We report that the natural product cucurbitacin E inhibits actin depolymerization and show that its...

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Detalhes bibliográficos
Main Authors: Sörensen, Pia M., Iacob, Roxana E., Fritzsche, Marco, Engen, John R., Brieher, William M., Charras, Guillaume, Eggert, Ulrike S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448819/
https://ncbi.nlm.nih.gov/pubmed/22724897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb300254s
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