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Catalytic Coupling of Arene C-H Bonds and Alkynes for the Synthesis of Coumarins: the Substrate Scope and Application to the Development of Neuroimaging Agents

C-H bond functionalization offers strategically novel approaches to complex organic compounds, however many C-H functionalization reactions suffer from poor compatibility with Lewis basic functional groups; especially amines, which are often essential for biological activity. This study describes a...

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Detalhes bibliográficos
Main Authors: Vadola, Paul A., Sames, Dalibor
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448786/
https://ncbi.nlm.nih.gov/pubmed/22768913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo3006842
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