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Pharmacological blockade of adenosine A(2A) receptors diminishes scarring

Adenosine A2A receptor (A(2A)R) stimulation promotes wound healing and is required for the development of fibrosis in murine models of scleroderma and cirrhosis. Nonetheless, the role of A(2A)R in the formation of scars following skin trauma has not been explored. Here, we examined the effect of pha...

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Hlavní autoři: Perez-Aso, Miguel, Chiriboga, Luis, Cronstein, Bruce N.
Médium: Artigo
Jazyk:Inglês
Vydáno: Federation of American Societies for Experimental Biology 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448776/
https://ncbi.nlm.nih.gov/pubmed/22767233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-209627
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