Aquaporin-1 Translocation and Degradation Mediates the Water Transportation Mechanism of Acetazolamide

BACKGROUND: Diuretic agents are widely used on the treatment of water retention related diseases, among which acetazolamide (AZA) acts originally as a carbonic anhydrase (CA) inhibitor. Aquaporin-1 (AQP1) being located in renal proximal tubules is required for urine concentration. Previously our lab...

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Detaylı Bibliyografya
Asıl Yazarlar: Zhang, Jianzhao, An, Yu, Gao, Junwei, Han, Jing, Pan, Xueyang, Pan, Yan, Tie, Lu, Li, Xuejun
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2012
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448731/
https://ncbi.nlm.nih.gov/pubmed/23029347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045976
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