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Aquaporin-1 translocation and degradation mediates the water transportation mechanism of acetazolamide.
BACKGROUND: Diuretic agents are widely used on the treatment of water retention related diseases, among which acetazolamide (AZA) acts originally as a carbonic anhydrase (CA) inhibitor. Aquaporin-1 (AQP1) being located in renal proximal tubules is required for urine concentration. Previously our lab...
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| Huvudupphovsmän: | , , , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Public Library of Science (PLoS)
2012-01-01
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| Serie: | PLoS ONE |
| Länkar: | http://europepmc.org/articles/PMC3448731?pdf=render |
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