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Illuminating the Off-Pathway Nature of the Molten Globule Folding Intermediate of an α-β Parallel Protein

Partially folded protein species transiently form during folding of most proteins. Often, these species are molten globules, which may be on- or off-pathway to the native state. Molten globules are ensembles of interconverting protein conformers that have a substantial amount of secondary structure,...

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Autori principali: Lindhoud, Simon, Westphal, Adrie H., Borst, Jan Willem, van Mierlo, Carlo P. M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448718/
https://ncbi.nlm.nih.gov/pubmed/23029219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045746
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