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Illuminating the Off-Pathway Nature of the Molten Globule Folding Intermediate of an α-β Parallel Protein

Partially folded protein species transiently form during folding of most proteins. Often, these species are molten globules, which may be on- or off-pathway to the native state. Molten globules are ensembles of interconverting protein conformers that have a substantial amount of secondary structure,...

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Bibliographic Details
Main Authors: Lindhoud, Simon, Westphal, Adrie H., Borst, Jan Willem, van Mierlo, Carlo P. M.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448718/
https://ncbi.nlm.nih.gov/pubmed/23029219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045746
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