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Lamin A/C Mutants Disturb Sumo1 Localization and Sumoylation in Vitro and in Vivo
A-type lamins A and C are nuclear intermediate filament proteins in which mutations have been implicated in multiple disease phenotypes commonly known as laminopathies. A few studies have implicated sumoylation in the regulation of A-type lamins. Sumoylation is a post-translational protein modificat...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3448699/ https://ncbi.nlm.nih.gov/pubmed/23029315 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045918 |
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