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Reduced Cellular Susceptibility to In Vitro HIV Infection Is Associated with CD4+ T Cell Quiescence

BACKGROUND: HIV preferentially establishes productive infection in activated CD4+ T cells. Since proportions of activated CD4+ T cells vary between individuals, this study aimed to determine if individuals with a greater proportion of activated CD4+ T cells would be more susceptible to in vitro HIV...

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Detalhes bibliográficos
Main Authors: Card, Catherine M., Rutherford, W. John, Ramdahin, Suzie, Yao, Xiaojian, Kimani, Makobu, Wachihi, Charles, Kimani, Joshua, Plummer, Francis A., Ball, T. Blake, Fowke, Keith R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448692/
https://ncbi.nlm.nih.gov/pubmed/23029309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045911
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